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Journal of Clinical and Applied Neurosciences                            Volume 2; Issue 1                                   Jan-Jun 2017
CASE REPORT
Discordant Encephalocele in Monozygotic Twins in Kaduna, Nigeria: A Case Report
Danjuma SALE, Stephen A KACHE

AFFILIATION
Department of Surgery
Barau Dikko Teaching Hospital, Kaduna State University, Kaduna,
NIGERIA

CORRESPONDING AUTHOR
Danjuma SALE
Department of Surgery
Barau Dikko Teaching Hospital, Kaduna State University, Kaduna,
NIGERIA

Phone: +234 806 943 2297
Email: doplass@yahoo.com <mailto:doplass@yahoo.com>

DISCLOSURES:
No disclosures were made.

Received: 1st June, 2017
Accepted 29th June, 2017
ABSTRACT

Encephaloceles are a rare central nervous system congenital anomaly, and discordant encephalocele in monozygotic twins is very rarely reported in the literature. This is the first report of discordant encephalocele in monozygotic twins from our centre. We present the case of a 2-day old low birth weight male monozygotic first twin with occipital encephalocele, microcephaly and a right sided clonic seizure, which was diagnosed prenatally by ultrasound scan. He had no other associated congenital anomaly and the second twin was phenotypically normal. Computerised tomographic scan showed skull defect with herniation of brain tissue. He was worked up for surgery, had excision and repair under general anaesthesia, made a satisfactory post-operative recovery, and was discharged on an anticonvulsant. However, there was evidence of delayed developmental milestones compared to the other twin by 18months of age. This case suggests that there may be other non-genetic and non-systemic factors that could be responsible for the development of this congenital anomaly, encephalocele.






Keywords:
Multifactorial, neural tissue, sporadic dysraphic malformation